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KMID : 0360220160570040667
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Journal of the Korean Ophthalmological Society
2016 Volume.57 No. 4 p.667 ~ p.671
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A Case of Anterior Migration of Fragmented Dexamethasone Intravitreal Implant
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김병재:Kim Byung-Jae
김성재:Kim Seong-Jae/한용섭:Han Yong-Seop/서성욱:Seo Seong-Wook/박종문:Park Jong-Moon/유지명:Yoo Ji-Myong/정인영:Chung In-Young
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Abstract
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Purpose: To report a case of fragmentation and anterior migration occurred after dexamethasone intravitreal implant (Ozurdexⓡ, Allergan, Irvine, CA, USA) injection in a branch retinal vein occlusion patient.
Case summary: A 66-year-old male was referred for blurred vision. He received cataract surgery in 1986 and was diagnosed with central retinal vein obstruction in 2011 in the right eye. For treatment of macular edema, dexamethasone intravitreal implant was performed in the right eye. One week after implantation, a fragment of the dexamethasone implant migrated to the anterior chamber with corneal edema and surgical removal was performed immediately. One day after removal, the remaining fragmented implant migrated to the anterior chamber and corneal edema still existed. The fragmented implant was removed with anterior chamber irrigation. After removal, corneal edema improved and visual acuity was recovered.
Conclusions: Anterior migrated dexamethasone implant could induce corneal complications, such as corneal edema and corneal decompensation and might lower the corneal endothelial cell even if immediately removed. We report a case of corneal edema, which was induced by anterior migration of a fragmented dexamethasone implant and recovered with immediate surgical removal.
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KEYWORD
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Anterior chamber migration, Corneal edema, Dexamethasone intravitreal implant, Fragmentation, Ozurdexⓡ
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